Compatibility «Exedrin» and «Vitrum Plus Junior»

• Interactions Exedrin with Vitrum Plus Junior

  • Dangerous interactions
    • ⓘ Inducers of microsomal liver enzymes or potentially hepatotoxic substances (for example, alcohol, rifampicin, isoniazid, hypnotics and antiepileptic drugs, including phenobarbital, phenytoin and carbamazepine) increase the toxicity of paracetamol, can lead to liver damage even with non-toxic doses of paracetamol, therefore liver function should be monitored.
  • Negative interactions
    • ⓘ Salicylates (N02BA) + Ammonium chloride, calcium chloride and other drugs that increase urine acidity => Increased action of salicylates up to the development of salicylism phenomena (the appearance of tinnitus, hearing loss).
    • ⓘ Increases the concentration of salicylates in the blood (increases the risk of crystalluria), ethinyl estradiol, benzylpenicillin and tetracyclines, reduces oral contraceptives.
    • ⓘ Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline drinks reduce absorption and assimilation.
    • ⓘ Quinoline preparations, calcium chloride, salicylates, corticosteroids deplete vitamin C reserves with prolonged use.
    • ⓘ Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline drinks reduce the absorption and assimilation of ascorbic acid.
    • ⓘ Ascorbic acid increases the risk of crystalluria in the treatment of short-acting salicylates and sulfonamides, slows down the excretion of acids by the kidneys, increases the excretion of drugs with an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood.
    • ⓘ Quinoline preparations, calcium chloride, salicylates, glucocorticosteroids deplete ascorbic acid reserves with prolonged use.
    • ⓘ Antacids containing magnesium and/or aluminum slow down and worsen the absorption of acetylsalicylic acid.
    • ⓘ The excretion of acetylsalicylic acid increases with urine alkalinization, which can occur when taking some antacids.
    • ⓘ Salicylates and HA reduce the risk of side effects.
    • ⓘ Increases the effect of indirect anticoagulants (coumarin derivatives) and the likelihood of liver damage with hepatotoxic drugs.
  • Positive interactions
    • ⓘ Enhances the effect of steroid and NSAIDs, cardiac glycosides, reduces the toxicity of the latter, as well as vitamins A and D.
    • ⓘ Vitamin E enhances the effect of glucocorticosteroid drugs, nonsteroidal anti-inflammatory drugs, and cardiac glycosides.
  • Unclear interactions
    • ⓘ Acetylsalicylic acid + Ascorbic acid analgin and citramon are used together in 12 preparations.
    • ⓘ Antacids.
    • ⓘ Ascorbic acid + Caffeine analgin and citramon are used together in 15 preparations.
    • ⓘ Nicotinamide + Caffeine analgin and citramon are used together in 5 preparations.
    • ⓘ Vitamin E + Caffeine analgin and citramon are used together in Geriatrix, Three-T Fat Burner, MR. HHOP.
    • ⓘ Riboflavin + Caffeine analgin and citramon are used together in Geriatrix, Orsoslim, MR. HHOP.
    • ⓘ Calcium pantothenate + Caffeine analgin and citramon are used together in Geriatrix, MR. HHOP.
    • ⓘ Folic acid + Caffeine analgin and citramon are used together in 4 preparations.
    • ⓘ Colecalciferol + Caffeine analgin and citramon are used together in MR. HHOP.
    • ⓘ Cyanocobalamin + Caffeine analgin and citramon are used together in Geriatrix, Three-T Fat Burner.
    • ⓘ Pyridoxine + Caffeine analgin and citramon are used together in 4 preparations.
    • ⓘ Thiamine + Caffeine analgin and citramon are used together in 5 preparations.
    • ⓘ Paracetamol + Ascorbic acid analgin and citramon are used together in 87 preparations.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

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Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
• Why do I need to
  • Avoid dangerous prescriptions for your patients.
  • Check the contraindications.
  • Evaluate the safety of therapy in the treatment of children.
  • See the compatibility of drugs with alcohol (enter it as a drug).
  • Point the doctor to the found interaction - you may need to adjust the therapy.
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• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,041,552 possible combinations of drugs and their components were found 412,577 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-06-18

Category - medicine