Compatibility «Ацетилсалициловая кислота-ЛекТ» and «Золасан Т»

• Interactions Ацетилсалициловая кислота-ЛекТ with Золасан Т

  • Dangerous interactions
    • ⓘ Although in clinical trials of the ophthalmic solution of dorzolamide hydrochloride, no violations of CSF and electrolyte balance have been reported, these violations have been reported with oral administration of carbonic anhydrase inhibitors and in some cases led to drug interaction (for example, toxicity associated with high-dose salicylate therapy).
    • ⓘ Although clinical trials of dorzolamide hydrochloride in the form of an ophthalmic solution did not report violations of CSF and electrolyte balance, such violations were noted with oral administration of carbonic anhydrase inhibitors and in some cases caused a number of drug interactions (for example, the manifestation of toxicity associated with high doses of salicylates).
    • ⓘ However, similar phenomena have been observed with the use of CA inhibitors, in pm and as a result of drug-drug interaction with other drugs (as a manifestation of toxicity against the background of taking high doses of salicylates).
    • ⓘ Increased toxicity may occur when taking high doses of acetylsalicylic acid.
  • Negative interactions
    • ⓘ NSAIDs weaken the hypotensive effect.
  • No interactions
    • ⓘ In clinical studies, dorzolamide was prescribed in combination with other drugs without negative manifestations of drug-drug interaction, in pm with timolol and betaxolol for topical use in ophthalmology, as well as drugs for systemic use: ACE inhibitors, BCC, diuretics, NSAIDs (including acetylsalicylic acid), hormones (estrogen, insulin, thyroxine).
  • Unclear interactions
    • ⓘ High-dose salicylate therapy.
    • ⓘ Acetazolamide (carbonic anhydrase inhibitor).

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

Video instruction

▶

Look at ▶Youtube

Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
• Why do I need to
  • Avoid dangerous prescriptions for your patients.
  • Check the contraindications.
  • Evaluate the safety of therapy in the treatment of children.
  • See the compatibility of drugs with alcohol (enter it as a drug).
  • Point the doctor to the found interaction - you may need to adjust the therapy.
  • Do you need an API for interactions/drug analogues for your project? Write to us.
• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,041,552 possible combinations of drugs and their components were found 412,577 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-06-18

Category - medicine